Welcome to ANApatterns.org, the official website for the International Consensus on Antinuclear Antibody (ANA) Patterns (ICAP). ICAP was initiated as a workshop aiming to thoroughly discuss and to promote consensus regarding the richness in nuances of morphological patterns observed in the indirect immunofluorescence assay on HEp-2 cells. The ICAP initiative was implemented at the 12th International Workshop on Autoantibodies and Autoimmunity (IWAA) by members of the Autoantibody Standardization Committee (ASC), a subcommittee of the International Union of Immunological Societies (IUIS) Quality Assessment and Standardization Committee and affiliated with the Centers for Diseases Control and Prevention (CDC). The ICAP committee is operating as an ASC sub-committee.

Citation for this work: E.K.L. Chan, J. Damoiseaux, O.G. Carballo, K. Conrad, W. de Melo Cruvinel, P.L.C. Francescantonio, M.J. Fritzler, I. Garcia-De La Torre, M. Herold, T. Mimori, M. Satoh, C.A. von Mühlen, and L.E.C. Andrade. Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns (ICAP) 2014-2015 (Front. Immunol. 2015, Aug 20;6:412).

Representative images, based on pixel dimension, resolution, and size, were submitted online by ICAP members. For each pattern, between 2 to >10 images were submitted. Most patterns had average 5 to 8 images. More than ten ICAP members voted for the best three images representing each pattern and the top two images for each pattern are displayed on this web site. (For an introduction of the website with some graphic images, click here.)

Announcements and Updates
Tue, 07 Jan 20

Information from the ICAP clinical relevance publication (Damoiseaux et al, Ann Rheum Dis 78: 879-89, 2019) is now incorporated to the website.

Mon, 04 Mar 19

The 5th ICAP Workshop will be held on September 9, 2019 in Dresden, one day prior to the 14th Dresden Symposium on Autoantibodies

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Sat, 16 Feb 19

The complete translation draft to Russian goes online. 

Wed, 30 Jan 19

"Clinical relevance of HEp-2 indirect immunofluorescent patterns: the International Consensus on ANA patterns (ICAP) perspective”

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Fri, 12 Oct 18

ICAP COURSE in Shenzhen, China

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Online since 19 May 2015